详细描述:
Phospho-IRS-1 (Ser636/639)抗体识别内源性的Ser636/639磷酸化的IRS-1蛋白水平。此抗体与其它相关磷酸化蛋白没有交叉反应。该多克隆抗体用与人类IRS-1中Serine636/639位点附近的氨基酸序列对应的人工合成磷酸化肽段免疫动物而制成。该抗体使用蛋白A和蛋白亲和层析纯化制得。Phospho-IRS-1 (Ser636/639) Antibody detects endogenous levels of IRS-1 only when phosphorylated at Ser636/639. This antibody does not cross-react with other related phospho-proteins. Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding serine 636/639 of human IRS-1. Antibodies are purified by protein A and peptide affinity chromatography.