详细描述:
Species predicted to react based on 100% sequence homology: Bovine, Dog, Pig。该抗体能够检测 活化的Asp175 附近剪切的caspase-3大片段(17/19 kDa)。该抗体不能识别全长的caspase-3和其他caspase裂解产物。该多克隆抗体是采用合成的人源caspases Asp175氨基酸氨基末端序列相对应的肽段免疫动物后制备获得。抗体通过蛋白A和肽段亲和层析而纯化。Cleaved Caspase-3 (Asp175) Antibody detects endogenous levels of the large fragment (17/19 kDa) of activated caspase-3 resulting from cleavage adjacent to Asp175. This antibody does not recognize full length caspase-3 or other cleaved caspases.Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to amino-terminal residues adjacent to (Asp175) in human caspase-3. Antibodies are purified by protein A and peptide affinity chromatography.