详细描述：
Nucleic acid hybridization of a nucleic acid probe to a target sequence immobilized on a solid support such as a nylon membrane is a powerful technique routinely used in the analysis of gene structure and expression and in the diagnosis of disease. Factors that affect the rate and efficiency of nucleic acid binding to a target sequence include hybridization time, temperature, concentration of the target sequence and concentration of the probe. Other variables which improve the hybridization reaction are the use of rate enhancers and blocking agents to suppress nonspecific hybridization. QuikHyb hybridization solution* was developed for use in Southern, Northern, slot-blot and plaque-lift formats using randomly labeled radioactive and nonradioactive nucleic acid probes. This easy-to-use solution reduces the time required for hybridization from the customary 12–24 hours down to 1–2 hours, resulting in sensitive detection of target sequences.
