Phospho-Estrogen Receptor α (Ser118) (16J4) Mouse mAb
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只有当丝氨酸(118位)磷酸化时,Phospho-Estrogen Receptor alpha (Ser118) (16J4) Mouse mAb能够检测内源性水平的雌激素受体α。它不与磷酸化的雌激素受体β发生交叉反应。该单克隆抗体通过用合成磷酸肽免疫动物制备,该合成磷酸肽是人雌激素受体α丝氨酸(118位)附近的残基。Phospho-Estrogen Receptor alpha (Ser118) (16J4) Mouse mAb detects endogenous levels of estrogen receptor alpha only when phosphorylated at serine 118. It does not cross-react with phosphorylated estrogen receptor beta.Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser118 of human ER alpha.