详细描述:
Species predicted to react based on 100% sequence homology: Mouse, Rat.Phospho-Gab1 (Tyr627) (C32H2) Rabbit mAb兔单抗能够检测内源性的酪氨酸(627位点)磷酸化的Gab1蛋白。抗体也可以与磷酸化的Gab2及磷酸化的Gab3或者活化的受体酪氨酸激酶(RTKs)发生交叉反应。该单克隆抗体是由合成与人源Gab1蛋白Tyr627的周围序列相对应的磷酸化肽段免疫动物而生产的。Phospho-Gab1 (Tyr627) (C32H2) Rabbit mAb detects endogenous levels of Gab1 only when phosphorylated at Tyr627. The antibody may cross-react with phosphorylated Gab2 or Gab3, or with activated receptor tyrosine kinases (RTKs).Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr627 of human Gab1.