详细描述：
ROS1 (D4D6) 兔单抗能够识别内源性水平的总ROS1蛋白。当用western blot进行分析时，该抗体不与其他相关蛋白发生交叉反应。请注意，染色可能在ROS1重排的肺癌，巨噬细胞/巨细胞，反应性Ⅱ型肺细胞增生，上皮细支气管上皮化生区域可见。在胆管癌，肝癌和肾脏中已观察到未知特异性的染色。单克隆抗体是通过用一个蛋白免疫动物而制备的，该蛋白是人ROS1蛋白羧基末端区域的残基。ROS1 (D4D6) Rabbit mAb recognizes endogenous levels of total ROS1 protein. This antibody does not cross-react with other related proteins when analyzed by western blot. Please note that staining may be observed in ROS1 rearranged lung carcinomas, macrophages/giant cells, reactive type II pneumocyte hyperplasia, and the epithelium in areas of bronchiolar metaplasia. Staining of unknown specificity has been observed in cholangiocarcinoma, hepatocellular carcinoma, and kidney tissues.Monoclonal antibody is produced by immunizing animals with a protein corresponding to residues in the carboxy terminal domain of the human ROS1 protein.
