详细描述:
ALK (D5F3) XP®兔单抗即使在低表达水平下能够检测内源性水平的总ALK蛋白以及ALK融合蛋白,如EML4-ALK变体和NPM-ALK。该抗体不与其他家族成员发生交叉反应。该单克隆抗体通过用重组蛋白免疫动物制备,该重组蛋白是人ALK羧基末端的残基。ALK (D5F3) XP® Rabbit mAb detects endogenous levels of total ALK protein as well as ALK fusion proteins, such as EML4-ALK variants and NPM-ALK, even at low levels. This antibody does not cross-react with other family members.Monoclonal antibody is produced by immunizing animals with recombinant protein corresponding to residues in the carboxy terminus of human ALK.