详细描述:
磷酸化PDGF Receptor α (Tyr1018) 抗体仅在Tyr1018被磷酸化后才能检测到PDGFRα的存在。本抗体不与活化的PDGFRβ发生交叉反应,但可能与包括EGFR在内的其他酪氨酸位点磷酸化的酪氨酸激酶有交叉反应。多克隆抗体通过用多肽免疫动物得到,该磷酸化多肽是根据人的PDGFRα蛋白Tyr1018附近的氨基酸序列合成的。抗体经过protein A和亲和层析纯化。Phospho-PDGF Receptor α (Tyr1018) Antibody detects PDGFRα only when phosphorylated at Tyr1018. The antibody does not cross-react with activated PDGFRβ. But it may cross-react with other tyrosine phosphorylated protein tyrosine kinases including EGF receptor.Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1018 of human PDGFRα. Antibodies are purified by protein A and peptide affinity chromatography.