详细描述:
Nonphospho-4E-BP1 (Thr46) (87D12) Rabbit mAb兔单抗检测仅在Thr46位点去磷酸化的内源性4E-BP1蛋白水平。这个抗体与在相同的位点去磷酸化的4E-BP2和4E-BP3蛋白发生交叉反应。通过人工合成人源4E-BP1 蛋白Thr46位点附近序列的多肽来免疫动物从而制备单克隆抗体。Nonphospho-4E-BP1 (Thr46) (87D12) Rabbit mAb detects endogenous levels of 4E-BP1 only when dephosphorylated at Thr46. The antibody cross-reacts with 4E-BP2 and 4E-BP3 dephosphorylated at equivalent sites.Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Thr46 of human 4E-BP1.
应用范围:W F IF-IC; 反应种属:Human,Mouse,Rat,Monkey; 灵敏度:Endogenous; MW (kDa):15-20; Isotype:Rabbit IgG; 标记:无标记。