详细描述:
Notch3 (D11B8)Rabbit mAb识别内源性的总Notch3蛋白。此抗体可以识别Notch3的270 kDa的全长蛋白(FL)和90 kDa的截短蛋白(NTM),这个截短蛋白包含一个短的胞外结构,跨膜区域和胞内区域。合成与人Notch3蛋白邻近Glu2312氨基酸残基序列一致的肽段,免疫动物获得单克隆抗体。Notch3 (D11B8) Rabbit mAb detects endogenous levels of total Notch3 protein. The antibody recognizes both full-length (FL) Notch3 at 270 kDa and a truncated protein (NTM) containing a short extracellular region, the transmembrane domain and the intracellular region at 90 kDa.Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Glu2312 of human Notch3 protein.