详细描述：
Species predicted to react based on 100% sequence homology: Mouse, Rat。只有当Tyr1078（相当于NPM-ALK中的Tyr138）磷酸化时，磷酸化ALK (Tyr1078) (D28B4) 兔单抗能够识别内源性水平的ALK。该抗体可能与其他过量表达的磷酸化酪氨酸激酶如EGFR和Src，发生交叉反应。该单克隆抗体是通过用合成磷酸肽免疫动物而制备的，该合成磷酸肽是人ALK蛋白Tyr1078附近的残基。Phospho-ALK (Tyr1078) (D28B4) Rabbit mAb recognizes endogenous levels of ALK only when phosphorylated at Tyr1078, which is equivalent to Tyr138 of NPM-ALK. This antibody may cross-react weakly with other overexpressed phospho-tyrosine kinases such as EGFR and Src.Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1078 of human ALK protein.
