详细描述:
只有当丝氨酸(345和181位)磷酸化时,Phospho-Progesterone Receptor (Ser345) Antibody能够分别识别内源性水平的孕酮受体B(PR-B)和孕酮受体A(PR-A)蛋白。该抗体不与其他孕酮受体家族成员发生交叉反应。该多克隆抗体通过用合成磷酸肽免疫动物制备,该合成磷酸肽是人孕酮受体蛋白B(PR-B)蛋白丝氨酸(345位)附近的残基。抗体由蛋白A和肽亲和层析纯化。Phospho-Progesterone Receptor (Ser345) Antibody recognizes endogenous levels of progesterone receptor B (PR-B) and progesterone receptor A (PR-A) proteins only when phosphorylated at Ser345 and Ser181, respectively. This antibody does not cross-react with other progesterone receptor family members.Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser345 of human progesterone receptor B (PR-B) protein. Antibodies are purified by protein A and peptide affinity chromatography.