详细描述:
Phospho-FoxO3a (Ser253) (D18H8) Rabbit mAb兔单抗识别仅在Ser253位点被磷酸化的内源性FoxO3a。该抗体可能与过表达并在Ser251位点被磷酸化的FoxO1以及过表达并在Ser197位点被磷酸化的FoxO4发生交叉反应。单克隆抗体由合成磷酸肽段免疫动物产生,该肽段与人从FoxO3a蛋白的Ser253邻近残基序列一致。Phospho-FoxO3a (Ser253) (D18H8) Rabbit mAb detects endogenous levels of FoxO3a only when phosphorylated at Ser253. This antibody may cross-react with FoxO1 when overexpressed and phosphorylated at Ser251 or FoxO4 when overexpressed and phosphorylated at Ser197.Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser253 of human FoxO3a protein.