BHQ-10是一种水溶性黑暗淬灭剂，其可被亲核基团活化并与之偶联，如蛋白质和肽上的胺。因其具有水溶性，因此可以减少与蛋白质的非特异性结合。按照荧光共振能量转移（FRET）原理，BHQ-10能够淬灭最大发射光接近516nm的荧光基团，例如荧光素（FITC是异硫氰酸荧光素）。
BHQ®-10 Succinimidyl Ester is a water soluble dark quencher that can be coupled to nucleophilic groups such as the amines on proteins and peptides. It has been formulated to provide water solubility and to reduce non-specific protein binding interactions with proteins. As a result of Fšrster Resonance Energy Transfer (FRET), BHQ-10 is expected to quench fluorophores that have emission maxima close to 516 nm, such as fluorescein (FITC is fluorescein isothiocyanate).
