化学合成的DNA如探针、引物和其它寡核苷酸具有广泛的应用，可用于PCR，基因组测序，SNP基因分型和基因合成等。
LGC Biosearch提供多种亚磷酰胺修饰的荧光报告染料和非荧光淬灭染料，可用于合成复杂的qPCR探针。
其专利的Black Hole Quencher®（BHQ®）染料亚磷酰胺能够有效淬灭所有荧光基团，因此从480nm到近红外可见光谱范围内发射荧光的任何报告染料都可以与其搭配使用。
CAL Fluor®和Quasar®荧光基团亚磷酰胺的发射光谱跨越可见光和近红外光谱，是多重实时qPCR的理想选择。
此外，LGC Biosearch还提供多种修饰如生物素、氨基、巯基、间臂以及其它常用荧光染料的亚磷酰胺。这些亚酰胺可用于直接掺入修饰的寡核苷酸中。
Chemically synthesized DNA in the form of probes, primers and other oligonucleotides are used in a variety of applications such as PCR, genome sequencing, SNP genotyping, and gene synthesis.
To enable the synthesis of sophisticated probes for q-PCR, LGC Biosearch offers a broad range of, fluorophore reporter and non-fluorescing quencher phosphoramidites.
Our proprietary Black Hole Quencher®(BHQ®)dye phosphoramidites are designed to permit efficient quenching of all fluorophores making it possible to utilize reporter dyes that emit anywhere across the visible spectrum from 480 nm into the near IR.
Our CAL Fluor® and Quasar® dye phosphoramidites are fluorophores with emission spectra that span the visible and near infrared spectrum, making them ideal for multiplexed real time qPCR assays.
LGC Biosearch also offers modifications such as Biotin, Amine, Thiol, Spacers as well as other popular fluorescent dye phosphoramidites. These amidites can be used for direct incorporation into the modified oligonucleotide.
