详细描述：
LGC Biosearch提供多种多样的寡核苷酸化学修饰方式，修饰类型从碱基修饰到荧光报告基团和猝灭基团标记，修饰位置包括3'端修饰、5'端修饰以及内部修饰，可任意排列组合，种类丰比任何一家提供Oligo定制或引物合成的公司都要多。
The I-SH modification replaces the normal phosphate linker with a phosphorothioate. This is accomplished by replacing the standard iodine and water oxidation step by treatment with Beaucage’s reagent (3H-1,2-benzodithiol-3-one-1,1-dioxide). This modification prevents nuclease degradation of the internucleotide linkage.
Biosearch Technologies offers more modifications than any other custom oligo supplier. From modified bases to fluorescent reporter and quencher labels, Biosearch offers a complete array of modifications for 3', 5' and internal labeling.
